Set in a grimy, industrial version of 2015, Memory Run depicts an Earth dominated by the Life Corporation, a global entity that has effectively supplanted traditional government authority. The world is characterized by urban decay, overpopulation, and a stark divide between the corporate elite and the street-level resistance known as "The Union." In this vision of the future, the search for immortality has led to the development of technology capable of transferring human consciousness from one body to another.

The film’s central dynamic explores the commodification of the human form, where convicts and political dissidents are harvested as biological vessels for the wealthy. Unlike the original novel, Season of the Witch, which focused on the psychological implications of gender identity, the film leans into action-heavy cyberpunk tropes, portraying a society where the Mind, Body, and Soul are no longer considered an inseparable unit. Earth is presented as a bleak landscape where individual identity is a fragile data point that can be overwritten by corporate whim.

Technologically, the film predicts neural mapping and biometric tracking as tools of state control. While the actual year 2015 did not see the advent of full-body brain transplants, the film’s depiction of digital memory storage and the erosion of privacy through pervasive surveillance mirrors contemporary anxieties regarding data harvesting. The "Life Corp" headquarters serves as a metaphor for the impenetrable power of modern tech conglomerates, even if the film's 2015 lacks the ubiquitous connectivity of the real-world era.